powered by centersite dot net
Medications
Resources
Basic InformationLatest News
FDA May Limit 'Risk Info' in Direct-to-Consumer TV Drug AdsHealth Tip: Throwing Out Leftover MedicineFDA Announces Recall of Some Liquid Pharmaceutical ProductsIs FDA Taking Close Enough Look at Fast-Tracked Drugs?U.S. Antidepressant Use Jumps 65 Percent in 15 YearsThe Fine Print on Medication Expiration DatesAmericans Taking More Prescription Drugs Than Ever: SurveyInappropriate Med Use High in Cognitively Impaired SeniorsA Reminder That Meds and Grapefruit Don't Always MixAspirin Responsiveness Can Change After Bariatric SurgerySome Medicines Boost Sensitivity to SunPainkiller Prescriptions More Prone to Errors If HandwrittenMedication Mistakes Have Doubled in U.S. Since 2000: StudyMarket Competition Linked to Change in Generic Drug PricesIs Your Child's 'Penicillin Allergy' Real?FDA Seeks to Increase Number of Generic Drugs on MarketWhen Is an Opioid Safe to Take?Lifesaving Drugs From Pfizer in Short Supply: FDALeading U.S. Doctors' Group Takes Aim at Rising Drug PricesU.S. Hospitals Still Prescribe Too Many Antibiotics: StudyBirth Control Pills Recalled Due to Danger of Unintended PregnancyNew Drugs Show Promise as First to Prevent MigraineMedication Adherence Up With Refill Synchronization ModelModified Vancomycin May Help Fight Bacterial ResistanceScientists Tweak Antibiotic to Boost Power Against 'Superbugs'New Cholesterol Fighting Meds Target Key GeneResearchers Say PDE5 Inhibitors Don't Cause MelanomaNearly a Third of Drugs Hit by Safety Issues After FDA ApprovalU.S. Moves to Avert Shortage of Yellow Fever VaccineOpioid Use by Iraq, Afghanistan War Vets Mirrors Rest of U.S.: StudyApril 29 Is National Prescription Drug Take Back DayERs Administering More Medications IntranasallyFDA Warns Against Children Taking Codeine, TramadolPhysicians Finding Ways to Work Around Cost of Rx MedicationsRuling Out Penicillin Allergy by Testing Inpatients Saves MoneyEpiPen Out-of-Pocket Costs More Than Doubled Over DecadeAACR: Regular Aspirin Use Linked to Lower Cancer MortalityFDA Approves Noctiva Nasal Spray for Nocturnal PolyuriaFDA Approves Odactra for House Dust Mite AllergiesHow Much Melatonin Is Really in That Supplement?Antidepressant Efficacy Varies for Depressive Symptom ClustersDo You Need an Antibiotic?'Off-Label' Antidepressants Common, But Where's the Evidence?Docs More Likely to Prescribe Antibiotics If Patients Expect ThemSimilar Adverse Event Risk for Typical, Atypical AntipsychoticsRx Adherence Reminders No More Effective at 'Fresh Start' DatesThink You're Allergic to Penicillin? Check AgainExcessive FDA Regulation Driving High Drug PricesOutcomes-Based Pricing Suggested for New, Costly DrugsPrices Skyrocket on Drugs Widely Used by Seniors: Report
Questions and AnswersVideosLinksBook Reviews
Related Topics

Anxiety Disorders
Depression: Depression & Related Conditions
Mental Disorders
Mental Health Professions

Do You Need an Antibiotic?

HealthDay News
by -- Mary Elizabeth Dallas
Updated: Feb 24th 2017

new article illustration

FRIDAY, Feb. 24, 2017 (HealthDay News) -- Hoping to lessen their misery, most people would like to know whether the respiratory illness they've got could be helped by an antibiotic.

The key to finding out may lie in your nose. Or, more specifically, the mucus in your nose.

Researchers from Duke Health in Durham, N.C., said they've identified a group of proteins that could be used to tell if an infection is caused by a virus, which triggers cold or flu.

Antibiotics can only fight bacterial infections, not viral illnesses.

When detected in specific quantities in the mucus of runny noses and inflamed throats, the proteins targeted in the new study were 86 percent accurate in confirming a viral infection, the scientists said.

"In the past, science has focused on identifying the pathogen someone is infected with in the blood or other sample," said study lead author Thomas Burke. He's director of technology advancement and diagnostics at Duke.

"Our approach flips the paradigm of how we look for infection. Instead of looking for the pathogen, we study the individual's response to that pathogen," Burke said in a health system news release.

For the trial, the researchers infected 88 healthy adults with a common strain of cold or flu virus. They also collected fluid samples from the volunteers' nasal passages.

Some participants didn't get sick, but those who did had a distinct set of 25 proteins in their noses, the study showed.

The researchers said their findings could lead to quick, noninvasive tests for upper respiratory infections that could be easily done in a doctor's office.

Senior author Dr. Geoffrey Ginsburg is director of the Duke Center for Applied Genomics & Precision Medicine. "Every day, people are taking time off from work, going to emergency rooms, urgent care or their primary care doctors with symptoms of an upper respiratory infection," he said.

"Looking for these proteins could be a relatively easy and inexpensive way of learning if a person has a viral infection, and if not, whether the use of antibiotics is appropriate," Ginsburg said.

Being able to quickly diagnose a viral infection could help limit the unnecessary use of antibiotics, helping to prevent the rise of antibiotic resistance, the researchers said.

Easier, cheaper tools to diagnose viral infections could also benefit those people with reduced access to health care, the researchers added.

"The protein targets offer a faster, more cost-effective model for rapid screening and diagnoses of viral infections," said Dr. Christopher Woods, a senior author of the study. He's associate director of applied genomics.

"If the data are verified, the model could be valuable in many circumstances, such as rural settings or developing countries with less convenient access to health care, or even as an airport screening tool during an outbreak of a particularly threatening strain of flu," Woods said.

The study was published recently in EBioMedicine.

More information

The U.S. National Library of Medicine provides more information on viral infections.